Ask About EXPAREL

Who Is EXPAREL for?

Non-opioid EXPAREL offers relief across a wide range of surgeries for adults and children, from oral surgery to ortho to cosmetic procedures. EXPAREL is a long-lasting, non-opioid injection given just once by your doctor during surgery to help manage pain.

Learn about the role EXPAREL can play in surgical recovery: https://www.exparel.com

Side Effects

Does EXPAREL Have Side Effects?

Side effects can occur with any medication; it is important not to ignore anything you might feel.

Some patients in clinical trials who received EXPAREL or other pain relievers experienced nausea, vomiting, fever, and/or constipation. Speak with your doctor right away if you get any of these more frequent side effects, or if you have questions about possible side effects.

Click here for more information

^INDICATION

^{EXPAREL® (bupivacaine liposome injectable suspension) is indicated to produce postsurgical local analgesia via infiltration in patients aged 6 years and older and regional analgesia in adults via an interscalene brachial plexus nerve block, sciatic nerve block in the popliteal fossa, and an adductor canal block. Safety and efficacy have not been established in other nerve blocks.}

^{IMPORTANT SAFETY INFORMATION}

^{EXPAREL should not be used in obstetrical paracervical block anesthesia.}

^{In studies in adults where EXPAREL was injected into a wound, the most common side effects were nausea, constipation,
and vomiting.}

^{In studies in adults where EXPAREL was injected near a nerve, the most common side effects were nausea, fever, headache, and constipation.}

^{In the study where EXPAREL was given to children, the most common side effects
were nausea, vomiting, constipation, low blood pressure, low number of red blood cells, muscle twitching, blurred vision, itching, and rapid heartbeat.}

^{EXPAREL can cause a temporary loss of feeling and/or loss of muscle movement. How much and how long the loss of feeling and/or muscle movement depends on where and how much of EXPAREL was injected and may last for up to 5 days.}

^{EXPAREL is not recommended to be
used in patients younger than 6 years old for injection into the wound, for patients younger than 18 years old for injection 
near a nerve, and/or in pregnant women.}

^{Tell your health care provider if you or your child has liver disease, since this may affect how the active ingredient (bupivacaine) 
in EXPAREL is eliminated from the body.}

^{EXPAREL should not be injected into the spine, joints, or veins.}

^{The active ingredient in EXPAREL can affect the nervous system and 
the cardiovascular system; may 
cause an allergic reaction; may cause damage if injected into the joints; 
and can cause a rare blood disorder. Please refer to full Prescribing Information.}

^{You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.}